[SCIENCE MONDAY] - MicroRNAs located on the X chromosome play a role in the regulation of the immune system and may contribute to sex differences in inflammatory and autoimmune diseases

This mini review provides an overview of the emerging role of X chromosome–encoded miRNAs in the regulation of immune function, highlighting how their differential expression contributes to sex-based differences in the incidence and severity of inflammatory and autoimmune diseases, and discussing their potential implications for the development of sex-specific diagnostic and therapeutic strategies.

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